Diane Marie Santangelo, 57, of Anderson, SC, passed away Monday, April 27, 2020 at Rainey Hospice House. Born November 7, 1962 in Erie, PA, she was the daughter of Linda Burke and the late Frank Santangelo. She was the spouse of the late Terry Charles Ayers. In addition to her mother, she is survived by her sister, Lisa Ann Estes (Richard) of Erie, PA; brothers-in-law, Tim Long of Anderson, SC and Michael Ayers (Nancy) of Anderson, SC; nieces, Stephanie Epps (Mac) and Summer Ayers (Jamie) both of Anderson, SC and Jennifer Estes of Erie, PA; nephews, Gabriel Ayers (Crystal) of Greenville, SC, Joseph Estes and Jared Estes both of Erie, PA; also survived by mother of Terry Ayers, Doris Ayers of Anderson, SC. In addition to her spouse and father, she was preceded in death by her sister-in-law, Cathy Long. A family cryptside service will be held on Friday, May 1, 2020 at 2:00 pm at Oaklawn Memorial with Rev. Dwight Greene officiating. In lieu of flowers, memorial contributions may be made to Hospice of the Upstate, 1835 Rogers Rd., Anderson, SC 29621 or Anderson Area Cancer Center, 2000 E. Greenville St., Suite 5000, Anderson, SC 29621. Events Cryptside Service Friday, May 1, 2020 2:00PM Oaklawn Memorial Gardens 2323 Highway 81 North Anderson, SC 29621 Email: Gail@mcdougaldfuneralhome.com,laurel@mcdougaldfuneralhome.com Phone: (864) 225-1636 Final Resting Place Oaklawn Memorial Gardens 2323 Highway 81 North Anderson, SC 29621